Fundus Autofluorescence imaging is the concept of using naturally occurring fluorescences from the retina to provide an indicator of a layer of the retina health.
Illuminating the retina with blue light causes the certain cellular component to glow without injecting any dye. This glow returning from the retina can be used to create a black and white image which can be interpreted by its recognizing characteristic patterns.
Fundus Autofluorescence patterns may be linked to disease progression in patients with age-related macular degeneration and may thereby help the clinician determine therapeutic courses in future. Macular degeneration, retinitis pigmentosa, central serous chorioretinopathy and macular dystrophies are the areas in which Fundus Autofluorescence have been used.